Based on daily precipitation data from 1960 to 2019 and hourly precipitation data in September 2019 from 109 meteorological stations in Shanxi Province and reanalysis data from European Centre of Medium-Range Weather Forecasts, the anomaly characteristics of the extremely regional rainstorm in central and southern Shanxi from 10 to 11 September 2019 and its causes were analyzed. The results are as follows: (1) The precipitation process affected a large area and lasted a long time, extreme daily precipitation events occurred at 46 stations, the daily precipitation of 11 stations exceeded the historical extreme value in September. (2) The water vapor, thermal and dynamic conditions in the middle and lower troposphere were better than the average state of regional rainstorm processes in the middle and south region of Shanxi since 1980, absolute values of normalized anomaly (|N|) of different physical quantities were higher than 2.5 and the upper quartile of historical data, especially for the water vapor and thermal conditions anomaly. (3) The subtropical high was anomalously strong and moved northward and westward, which led to abnormally strong water vapor and energy transport in mid-low troposphere, water vapor input in the western and southern boundaries of central and southern Shanxi Province played an important role in occurrence and development of extreme precipitation. (4) There was the potential instability in the inclined warm-moist southwesterly, warm shear line on 700 hPa and surface cold front initiated the convection, “train effect” produced due to echo moving continuously through heavy rain area. The stabilized shear line and abnormally cold wedge in lower troposphere provided sustained dynamic condition, abnormally plentiful vapor and its convergence maintained sustainably, which was the main causes of the extreme regional rainstorm, and the large range of physical quantities anomaly was the main influence factor of it.